HSP90AA1 Antibody / HSP90 alpha
HSP90 alpha is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P07900
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human HSP90 alpha / HSP90AA1 was used as the immunogen for the HSP90AA1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CCF-8
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the HSP90AA1 antibody at -20oC.
Limitations
This HSP90AA1 antibody is available for research use only.
Storage Conditions
Store the HSP90AA1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the HSP90AA1 antibody should be determined by the researcher.
Location
Cell membrane, cytoplasmic, nuclear
Image Legend
Western blot testing of human HeLa cell lysate with HSP90AA1 antibody. Predicted molecular weight: 86-90 kDa.
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