CD3 epsilon Antibody / CD3e
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P07766
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human CD3 epsilon / CD3E was used as the immunogen for the CD3 epsilon antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
EED-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD3 epsilon antibody at -20oC.
Limitations
This CD3 epsilon antibody is available for research use only.
Storage Conditions
Store the CD3 epsilon antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD3 epsilon antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with CD3 epsilon antibody. Predicted molecular weight ~23 kDa.
Documents
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MMP9 Recombinant Rabbit mAb, PerCP-Cy7 conjugated
