CD3e Antibody
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P07766
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide specific to mouse CD3 epsilon / CD3E was used as the immunogen for the CD3e antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
COB-3
Type
Recombinant
Applications
IHC-P
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD3e antibody at -20oC.
Limitations
This CD3e antibody is available for research use only.
Storage Conditions
Store the CD3e antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD3e antibody should be determined by the researcher.
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