CTSD Antibody / Cathepsin D
Cathepsin D / CTSD is an acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P07339
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Cathepsin D / CTSD was used as the immunogen for the CTSD antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CEF-3
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CTSD antibody at -20oC.
Limitations
This CTSD antibody is available for research use only.
Storage Conditions
Store the CTSD antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CTSD antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) MCF7 and 2) SK-BR-3 cell lysate with CTSD antibody. Expected molecular weight: 43-46 kDa and 28 kDa (heavy chain) .
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