Thyroid Peroxidase Antibody / TPO
The TPO gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA.
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
P07202
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human TPO / Thyroid peroxidase was used as the immunogen for the Thyroid Peroxidase antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AFFI-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Thyroid Peroxidase antibody at -20oC.
Limitations
This Thyroid Peroxidase antibody is available for research use only.
Storage Conditions
Store the Thyroid Peroxidase antibody at -20°C.
Product Datasheet
https://www.nsjbio.com/tds-pdf/thyroid-peroxidase-antibody-tpo-affi-20-rq5170
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Thyroid Peroxidase antibody should be determined by the researcher.
CAS Number
9000-83-3
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