Tyrosine Hydroxylase Antibody / TH

The protein encoded by the TH gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome.

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence: 1:50-1200

UniProt

P07101

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Tyrosine Hydroxylase / TH was used as the immunogen for the Tyrosine Hydroxylase antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ECA-20

Type

Recombinant

Applications

IHC-P, WB, IF

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the Tyrosine Hydroxylase antibody at -20oC.

Limitations

This Tyrosine Hydroxylase antibody is available for research use only.

Storage Conditions

Store the Tyrosine Hydroxylase antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Tyrosine Hydroxylase antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic, cell membrane

Image Legend

Immunofluorescent staining of FFPE rat PC-12 cells with Tyrosine Hydroxylase antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.