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Phospho-CDK1/2 Antibody (pT14)

Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.[1] They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. [Wiki]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200

UniProt

P06493

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthetic peptide specific to human CDK1/2 (surrounding phosphorylated T14) was used as the immunogen for the phospho-CDK1/2 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

DFH-3

Type

Recombinant

Applications

IHC-P, WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the phospho-CDK1/2 antibody (pT14) at -20oC.

Limitations

This phospho-CDK1/2 antibody (pT14) is available for research use only.

Storage Conditions

Store the phospho-CDK1/2 antibody (pT14) at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the phospho-CDK1/2 antibody (pT14) should be determined by the researcher.

Image Legend

Western blot testing of lysate from human HeLa cells treated with hydroxyurea, with phospho-CDK1/2 antibody (pT14) . Predicted molecular weight ~33 kDa.

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