CDC2 Antibody / CDK1
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P06493
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human CDK1 / CDC2 was used as the immunogen for the CDC2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BOI-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CDC2 antibody at -20oC.
Limitations
This CDC2 antibody is available for research use only.
Storage Conditions
Store the CDC2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CDC2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with CDC2 antibody. Predicted molecular weight ~33 kDa.
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