CDK1 Antibody / CDC2

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200

UniProt

P06493

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human CDK1 / CDC2 was used as the immunogen for the CDK1 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

BOH-3

Type

Recombinant

Applications

IHC-P, WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the CDK1 antibody at -20oC.

Limitations

This CDK1 antibody is available for research use only.

Storage Conditions

Store the CDK1 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the CDK1 antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human colon tissue with CDK1 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.