Hydroxyl-Histone H2A Antibody (Tyr39)
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:500-1:2000
UniProt
P04908
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Clonality
Monoclonal
Isotype
IgG
Clone
DED-8
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the hydroxyl-Histone H2A antibody (Tyr39) at -20oC.
Limitations
This hydroxyl-Histone H2A antibody (Tyr39) is available for research use only.
Storage Conditions
Store the hydroxyl-Histone H2A antibody (Tyr39) at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the hydroxyl-Histone H2A antibody (Tyr39) should be determined by the researcher.
Image Legend
Western blot testing of 1) mouse NIH3T3 and 2) human A549 cell lysate with hydroxyl-Histone H2A antibody (Tyr39) . Predicted molecular weight ~14 kDa.
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