CYBB Antibody / NOX2 / gp91phox
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000
UniProt
P04839
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Nox2 / CYBB was used as the immunogen for the CYBB antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
GOH-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CYBB antibody at -20oC.
Limitations
This CYBB antibody is available for research use only.
Storage Conditions
Store the CYBB antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CYBB antibody should be determined by the researcher.
Image Legend
Western blot testing of human MCF7 cell lysate with CYBB antibody. Predicted molecular weight ~65 kDa, can be observed at ~85 kDa.
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