Acetyl-p53 Antibody (Lys370)

Cellular tumor antigen p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Acetylation of the protein influences its tumor suppressor function.[UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P04637

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human p53 (surrounding acetylated K370) was used as the immunogen for the acetyl-p53 antibody (Lys370) .

Clonality

Monoclonal

Isotype

IgG

Clone

DEO-20

Type

Recombinant

Applications

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the acetyl-p53 antibody (Lys370) at -20oC.

Limitations

This acetyl-p53 antibody (Lys370) is available for research use only.

Storage Conditions

Store the acetyl-p53 antibody (Lys370) at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the acetyl-p53 antibody (Lys370) should be determined by the researcher.

Image Legend

Western blot testing of lysate from human HeLa cells treated with Trichostatin A, with acetyl-p53 antibody (Lys370) . Predicted molecular weight ~53 kDa.