HLA-DPB1 Antibody
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:5000
UniProt
P04440
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human HLA-DPB1 was used as the immunogen for the HLA-DPB1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AAEB-8
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the HLA-DPB1 antibody at -20oC.
Limitations
This HLA-DPB1 antibody is available for research use only.
Storage Conditions
Store the HLA-DPB1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the HLA-DPB1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Daudi cell lysate with HLA-DPB1 antibody. Predicted molecular weight ~27 kDa.
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