TK1 Antibody / Thymidine Kinase 1
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:5000-1:20000
UniProt
P04183
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Thymidine Kinase 1 was used as the immunogen for the TK1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AOBB-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the TK1 antibody at -20oC.
Limitations
This TK1 antibody is available for research use only.
Storage Conditions
Store the TK1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Thymidine Kinase 1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Molt4 cell lysate with TK1 antibody. Predicted molecular weight ~25 kDa.
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