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TK1 Antibody / Thymidine Kinase 1

The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:5000-1:20000

UniProt

P04183

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Thymidine Kinase 1 was used as the immunogen for the TK1 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AOBB-20

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the TK1 antibody at -20oC.

Limitations

This TK1 antibody is available for research use only.

Storage Conditions

Store the TK1 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Thymidine Kinase 1 antibody should be determined by the researcher.

Image Legend

Western blot testing of human Molt4 cell lysate with TK1 antibody. Predicted molecular weight ~25 kDa.

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