Apolipoprotein B Antibody / APOB
The APOB gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 (~240 kDa) and apoB-100 (~516 kDa) : the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P04114
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Apolipoprotein B / APOB was used as the immunogen for the Apolipoprotein B antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AOIH-1
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Apolipoprotein B antibody at -20oC.
Limitations
This Apolipoprotein B antibody is available for research use only.
Storage Conditions
Store the Apolipoprotein B antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.
Image Legend
Western blot testing of human serum lysate with Apolipoprotein B antibody. Predicted molecular weight ~516 kDa.
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