Phospho-Histone H2B Antibody
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
P02293
Host
Rabbit
Reactivity
Yeast
Immunogen
A synthetic peptide specific to yeast Histone H2B (surrounding pT129) was used as the immunogen for the phospho-Histone H2B antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
DEI-8
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the phospho-Histone H2B antibody at -20oC.
Limitations
This phospho-Histone H2B antibody is available for research use only.
Storage Conditions
Store the phospho-Histone H2B antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the phospho-Histone H2B antibody should be determined by the researcher.
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