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TG Antibody / Thyroglobulin

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:5000

UniProt

P01266

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Thyroglobulin / TG was used as the immunogen for the TG antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AFEI-20

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the TG antibody at -20oC.

Limitations

This TG antibody is available for research use only.

Storage Conditions

Store the TG antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the TG antibody should be determined by the researcher.

Image Legend

Western blot testing with TG antibody. Predicted molecular weight ~305 kDa.

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