CPAMD8 Antibody

CPAMD8 belongs to the complement component-3 (C3) / alpha-2-macroglobulin (A2M) family of proteins, which are involved in innate immunity and damage control. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. By genomic sequence analysis, the CPAMD8 gene is mapped to chromosome 19p13.3-p13.2.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q8IZJ3

Host

Rabbit

Reactivity

Human, Monkey

Immunogen

Amino acids R58-D234 from the human protein were used as the immunogen for the CPAMD8 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the CPAMD8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CPAMD8 antibody is available for research use only.

Storage Conditions

After reconstitution, the CPAMD8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the CPAMD8 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

Western blot testing of human 1) placenta, 2) T-47D, 3) U-2 OS, 4) K562, 5) ThP-1 and 6) monkey COS-7 lysate with CPAMD8 antibody at 0.5ug/ml. Predicted molecular weight ~207 kDa.