BMP15 Antibody / Bone morphogenetic protein 15

Bone morphogenetic protein 15 is a protein that in humans is encoded by the BMP15 gene. It is mapped to Xp11.22. It's mainly involved in folliculogenesis. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

O95972

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids KGTCLRVLRDGLNSPNHAIIQNLINQLVDQ from the human protein were used as the immunogen for the BMP15 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the BMP15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This BMP15 antibody is available for research use only.

Storage Conditions

After reconstitution, the BMP15 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the BMP15 antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human thyroid cancer with BMP15 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.