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C-Fos Antibody / FOS

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500

UniProt

P01100

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human c-Fos / FOS was used as the immunogen for the c-Fos antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

IIO-6

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the c-Fos antibody at -20oC.

Limitations

This c-Fos antibody is available for research use only.

Storage Conditions

Store the c-Fos antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the c-Fos antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HeLa and 2) RT4 cell lysate with c-Fos antibody. Expected molecular weight ~40 kDa, but may be observed at higher molecular weights due to phosphorylation.

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