TIMP1 Antibody

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P01033

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human TIMP1 was used as the immunogen for the TIMP1 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AAOD-20

Type

Recombinant

Applications

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the TIMP1 antibody at -20oC.

Limitations

This TIMP1 antibody is available for research use only.

Storage Conditions

Store the TIMP1 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the TIMP1 antibody should be determined by the researcher.

Image Legend

Western blot testing of human prostate cancer lysate with TIMP1 antibody. Expected molecular weight: 23-28 kDa depending on the level of glycosylation.