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C3 Antibody / Complement C3

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P01024

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Complement C3 was used as the immunogen for the C3 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AOHE-3

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the C3 antibody at -20oC.

Limitations

This C3 antibody is available for research use only.

Storage Conditions

Store the C3 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the C3 antibody should be determined by the researcher.

Image Legend

Western blot testing of human HepG2 cell lysate with C3 antibody. Expected molecular weight: ~185 kDa (alpha + beta chain), ~110 kDa (alpha chain), ~70 kDa (beta chain) .
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