Alpha 1 Antitrypsin Antibody / SERPINA1 / AAT

Alpha 1 Antitrypsin in an inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

P01009

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human SERPINA1 / Alpha 1 Antitrypsin was used as the immunogen for the Alpha 1 Antitrypsin antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

AOEF-19

Type

Recombinant

Applications

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the Alpha 1 Antitrypsin antibody at -20oC.

Limitations

This Alpha 1 Antitrypsin antibody is available for research use only.

Storage Conditions

Store the Alpha 1 Antitrypsin antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Alpha 1 Antitrypsin antibody should be determined by the researcher.

Image Legend

Western blot testing of human fetal kidney lysate with Alpha 1 Antitrypsin antibody. Expected molecular weight: 47-52 kDa depending on the level of glycosylation.