CLDN1 Antibody / Claudin 1
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95832
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Claudin 1 / CLDN1 was used as the immunogen for the CLDN1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ABEH-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CLDN1 antibody at -20oC.
Limitations
This CLDN1 antibody is available for research use only.
Storage Conditions
Store the CLDN1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CLDN1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human A431 cell lysate with CLDN1 antibody. Expected molecular weight: 20-23 kDa.
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