AIFM1 Antibody / AIF / Apoptosis-Inducing Factor
'Apoptosis-inducing factor 1, mitochondrial' functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95831
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human AIF / AIFM1 was used as the immunogen for the AIFM1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
GH-1
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the AIFM1 antibody at -20oC.
Limitations
This AIFM1 antibody is available for research use only.
Storage Conditions
Store the AIFM1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the AIFM1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human K562 cell lysate with AIFM1 antibody. Predicted molecular weight ~67 kDa.
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