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RIG-I Antibody / DDX58

Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:1000

UniProt

O95786

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human RIG-I was used as the immunogen for the RIG-I antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ACEA-4

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the RIG-I antibody at -20oC.

Limitations

This RIG-I antibody is available for research use only.

Storage Conditions

Store the RIG-I antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the RIG-I antibody should be determined by the researcher.

Image Legend

Western blot testing with RIG-I antibody. Expected molecular weight: 106-115 kDa.

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