RIG-I Antibody / DDX58
Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
O95786
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human RIG-I was used as the immunogen for the RIG-I antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACEA-4
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the RIG-I antibody at -20oC.
Limitations
This RIG-I antibody is available for research use only.
Storage Conditions
Store the RIG-I antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the RIG-I antibody should be determined by the researcher.
Image Legend
Western blot testing with RIG-I antibody. Expected molecular weight: 106-115 kDa.
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