Epac1 Antibody / RAPGEF3
The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95398
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Epac1 / RAPGEF3 was used as the immunogen for the Epac1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AEOG-18
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Epac1 antibody at -20oC.
Limitations
This Epac1 antibody is available for research use only.
Storage Conditions
Store the Epac1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Epac1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with Epac1 antibody. Predicted molecular weight ~104 kDa.
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