BMP11 Antibody / GDF11
Growth/differentiation factor 11, also called Bone morphogenetic protein 11, is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95390
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide specific to human BMP11 / GDF11 was used as the immunogen for the BMP11 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AOAG-7
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the BMP11 antibody at -20oC.
Limitations
This BMP11 antibody is available for research use only.
Storage Conditions
Store the BMP11 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the BMP11 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human HeLa and 2) rat C6 cell lysate with BMP11 antibody. Predicted molecular weight ~45 kDa.
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