KAT7 Antibody
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95251
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human KAT7 / HBO1 / MYST2 was used as the immunogen for the KAT7 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ADAE-11
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the KAT7 antibody at -20oC.
Limitations
This KAT7 antibody is available for research use only.
Storage Conditions
Store the KAT7 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the KAT7 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human MCF7, 2) mouse NIH3T3 and 3) rat C6 cell lysate with KAT7 antibody. Predicted molecular weight ~71 kDa.
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