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SLIT2 Antibody

Slit homolog 2 protein is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. [UniProt]

Product Specifications

Specifications

Western blot: 1:500-1:2000

UniProt

O94813

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human SLIT2 was used as the immunogen for the SLIT2 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ACGF-19

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the SLIT2 antibody at -20oC.

Limitations

This SLIT2 antibody is available for research use only.

Storage Conditions

Store the SLIT2 antibody at -20°C.

Product Datasheet

https://www.nsjbio.com/tds-pdf/slit2-antibody-acgf-19-rq4797

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the SLIT2 antibody should be determined by the researcher.

CAS Number

9000-83-3

Image Legend

Western blot testing of human SH-SY5Y cell lysate with SLIT2 antibody. Expected molecular weight: ~180-210 kDa (full length), ~140 kDa (N-terminal fragment), 55-60 kDa (C-terminal fragment) .
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