SLIT2 Antibody
Slit homolog 2 protein is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O94813
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human SLIT2 was used as the immunogen for the SLIT2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACGF-19
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the SLIT2 antibody at -20oC.
Limitations
This SLIT2 antibody is available for research use only.
Storage Conditions
Store the SLIT2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the SLIT2 antibody should be determined by the researcher.
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