PIAS1/2/3 Antibody
Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins act as transcriptional co-regulators with at least 60 different proteins in order to either activate or repress transcription. The transcription factors STAT, NF-κB, p73, and p53 are among the many proteins that PIAS interacts with. PIAS proteins have potential applications in cancer treatment and prevention. They may also play an important role in regulating immune system responses. [Wiki]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O75925
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human PIAS 1 & 2 & 3 was used as the immunogen for the PIAS1/2/3 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ABFA-16
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PIAS1/2/3 antibody at -20oC.
Limitations
This PIAS1/2/3 antibody is available for research use only.
Storage Conditions
Store the PIAS1/2/3 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PIAS1/2/3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HepG2 cell lysate with PIAS1/2/3 antibody. Predicted molecular weight: ~72 kDa (PIAS1) and ~68 kDa (PIAS2 & 3) .
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