Geminin Antibody / GMNN
Geminin inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
O75496
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Geminin / GMNN was used as the immunogen for the Geminin antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AEGO-7
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Geminin antibody at -20oC.
Limitations
This Geminin antibody is available for research use only.
Storage Conditions
Store the Geminin antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Geminin antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with Geminin antibody. Predicted molecular weight: 25-35 kDa.
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