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H2AFY Antibody / Macro H2A.1

'Core histone macro-H2A.1' is involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:5000

UniProt

O75367

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human H2AFY / macroH2A.1 was used as the immunogen for the H2AFY antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ADDI-8

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the H2AFY antibody at -20oC.

Limitations

This H2AFY antibody is available for research use only.

Storage Conditions

Store the H2AFY antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the H2AFY antibody should be determined by the researcher.

Image Legend

Western blot testing of human HepG2 cell lysate with H2AFY antibody. Predicted molecular weight ~40 kDa.

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