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ROCK2 Antibody

'Rho-associated protein kinase 2' (ROCK2) is a protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:5000

UniProt

O75116

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human ROCK2 was used as the immunogen for the ROCK2 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ACDH-18

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the ROCK2 antibody at -20oC.

Limitations

This ROCK2 antibody is available for research use only.

Storage Conditions

Store the ROCK2 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the ROCK2 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) human HeLa and 2) mouse RAW264 lysate with ROCK2 antibody. Predicted molecular weight ~161 kDa.

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