Phospho-NBS1 Antibody (pS343)
Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O60934
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human NBS1 / NBN (surrounding pS343) was used as the immunogen for the phospho-NBS1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BGI-14
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the phospho-NBS1 antibody at -20oC.
Limitations
This phospho-NBS1 antibody is available for research use only.
Storage Conditions
Store the phospho-NBS1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the phospho-NBS1 antibody should be determined by the researcher.
Image Legend
Western blot testing of etoposide-treated human Jurkat cell lysate with phospho-NBS1 antibody. Predicted molecular weight ~95 kDa.
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