P120 Catenin Antibody / CTNND1

P120 Catenin binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity) . Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

O60716

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Catenin delta 1 / p120 Catenin / CTNND1 was used as the immunogen for the p120 Catenin antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

GI-3

Type

Recombinant

Applications

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the p120 Catenin antibody at -20oC.

Limitations

This p120 Catenin antibody is available for research use only.

Storage Conditions

Store the p120 Catenin antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the p120 Catenin antibody should be determined by the researcher.

Image Legend

Western blot testing of human HeLa cell lysate with p120 Catenin antibody. Predicted molecular weight of isoform 1: 102-108 kDa and isoform 2: 95-102 kDa.