TAK1 Antibody / MAP3K7
The protein encoded by the MAP3K7 gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunofluorescence/Immunocytochemistry: 1:100-1:500
UniProt
O43318
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human MAP3K7/TAK1 was used as the immunogen for the TAK1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACHF-13
Type
Recombinant
Applications
IF/ICC, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the TAK1 antibody at -20oC.
Limitations
This TAK1 antibody is available for research use only.
Storage Conditions
Store the TAK1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the TAK1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with TAK1 antibody. Predicted molecular weight: 64-69 kDa, routinely observed at 78-82 kDa.
Frequently Asked Questions
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