BIRC5 Antibody / Survivin
The BIRC5 gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
O15392
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Survivin / BIRC5 was used as the immunogen for the BIRC5 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ABB-2
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the BIRC5 antibody at -20oC.
Limitations
This BIRC5 antibody is available for research use only.
Storage Conditions
Store the BIRC5 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the BIRC5 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Documents
Frequently Asked Questions
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