IKK alpha/beta Antibody
The IkappaB kinase complex is composed of three subunits each encoded by a separate gene: IKK alpha (also known as IKK1 and CHUK), IKK beta (also known as IKK2 and IKBKB), and IKK gamma (also known as NEMO/ and IKBKG) . The alpha- and beta- subunits together are catalytically active whereas the gamma-subunit serves a regulatory function. The IKKa and IKKb kinase subunits are homologous in structure, composed of a kinase domain, as well as leucine zipper and helix-loop-helix dimerization domains, and a carboxy-terminal NEMO-binding domain (NBD) . [Wiki]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
O15111
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide amino acid sequence specifc for and common to human IKK alpha and beta was used as the immunogen for the IKK alpha/beta antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
FCC-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the IKK alpha/beta antibody at -20oC.
Limitations
This IKK alpha/beta antibody is available for research use only.
Storage Conditions
Store the IKK alpha/beta antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the IKK alpha/beta antibody should be determined by the researcher.
Image Legend
Western blot testing of human A431 cell lysate with IKK alpha/beta antibody. Predicted molecular weight ~85 kDa.
Documents
Frequently Asked Questions
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