Neuropilin 1 Antibody / NRP1
The NRP1 encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
O14786
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human Neuropilin 1 / NRP1 was used as the immunogen for the Neuropilin 1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BGO-14
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Neuropilin 1 antibody at -20oC.
Limitations
This Neuropilin 1 antibody is available for research use only.
Storage Conditions
Store the Neuropilin 1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Neuropilin 1 antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse heart lysate with Neuropilin 1 antibody. Expected molecular weight: 102-130 kDa.
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