DR5 Antibody

The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:5000

UniProt

O14763

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ABFC-20

Type

Recombinant

Applications

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the DR5 antibody at -20oC.

Limitations

This DR5 antibody is available for research use only.

Storage Conditions

Store the DR5 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the DR5 antibody should be determined by the researcher.

Image Legend

Western blot testing of human HeLa cell lysate with DR5 antibody. Expected molecular weight: ~40 kDa (mature form) and ~48 kDa (precursor) . This protein may also be visualized at ~60 kDa.