DR5 Antibody
The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:5000
UniProt
O14763
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ABFC-20
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the DR5 antibody at -20oC.
Limitations
This DR5 antibody is available for research use only.
Storage Conditions
Store the DR5 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the DR5 antibody should be determined by the researcher.
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