LEC Antibody / HCC-4 / CCL16
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1) . This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, ELISA (Capture) : 1-5 µg/mL (human recombinant protein)
UniProt
O15467
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids Q24-Q120 from the human protein were used as the immunogen for the LEC antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (Capture)
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This LEC antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LEC antibody should be determined by the researcher.
Image Legend
Western blot testing of human A431 lysate with LEC antibody at 0.5ug/ml. Predicted molecular weight ~14 kDa.
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