TNF Receptor Antibody / TNFR1 / TNFRSF1A

Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), also known as TNFR1, is a protein that in humans is encoded by the TNFRSF1A gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. The TNFR1 gene is mapped to 12pter-cen. It encodes a protein of 455 amino acids. And this receptor can activate the transcription factor NF-kB, mediate apoptosis, and function as a regulator of inflammation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, ELISA (Capture) : 1-5 µg/mL (recombinant human protein)

UniProt

P19438

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids I22-T211 from the human protein were used as the immunogen for the TNF Receptor antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, ELISA (Capture)

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the TNF Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TNF Receptor antibody is available for research use only.

Storage Conditions

After reconstitution, the TNF Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the TNF Receptor antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE mouse colon tissue with TNF Receptor antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.