NOVA1 Antibody
RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. It is mapped to 14q12. This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P51513
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids T416-V509 from the human protein were used as the immunogen for the NOVA1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This NOVA1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NOVA1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE mouse brain tissue with NOVA1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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