CDT1 Antibody
Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC) . Required also for mitosis by promoting stable kinetochore-microtubule attachments. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
Q9H211
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide from human CDT1 was used as the immunogen for the CDT1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BO-3
Type
Recombinant
Applications
WB
Purity
Protein A affinity
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CDT1 antibody at -20oC.
Limitations
This CDT1 antibody is available for research use only.
Storage Conditions
Store the CDT1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CDT1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HEK293 lysate with CDT1 antibody at 0.5ug/ml. Predicted molecular weight ~60 kDa, commonly observed at 60-70 kDa.
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