What is the catalog number for COBRA1 Antibody?

The catalog number for COBRA1 Antibody is RQ4476.

What sizes are available for COBRA1 Antibody?

COBRA1 Antibody is available in the following size(s): 100 µg.

Is COBRA1 Antibody in stock?

COBRA1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

COBRA1 Antibody

Cofactor of BRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2), either NELF-C or NELF-D (TH1L), and NELF-E (RDBP) . NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1) and SPT5 (SUPT5H), to cause transcriptional pausing of RNA polymerase II. COBRA1 was initially identified in a yeast two-hybrid screen using the BRCT1 domain of BRCA1 as bait.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL (human recombinant protein)

UniProt

Q8WX92

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Human COBRA1 recombinant protein (amino acids M1-E252) was used as the immunogen for the COBRA1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the COBRA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This COBRA1 antibody is available for research use only.

Storage Conditions

After reconstitution, the COBRA1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the COBRA1 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Western blot testing of 1) rat kidney, 2) mouse kidney and 3) human MDA-MB-231 lysate with COBRA1 antibody at 0.5ug/ml. Predicted molecular weight ~66 kDa.