NPC2 Antibody / Niemann Pick C2
NPC2 is a protein associated with Niemann-Pick disease, type C. This gene is mapped to chromosome 14q24.3. It encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 2-5 µg/mL
UniProt
P61916
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids KSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVS from the human protein were used as the immunogen for the NPC2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This NPC2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NPC2 antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Collagen VII (COL7A1) (NM_000094) Human Over-expression Lysate
Prolactin Receptor (B6.2), Biotin conjugate, 0.1mg/mL
